There are many ways to customize Windows 10. So it depends on what you want to do with desktop. If you are into shell and theme customization then software like Stardock windowblinds can help you make many changes.
For example to make taskbar transparent, follow the steps below.
1. Go to start menu and click on settings app link.
2. Go to personalization section and select color.
3. Select "Make Start, taskbar, and action center transparent" option.
That's it. You can now make it more transparent. Also do search for one small app that is floating on the net that can help you adjust opacity of each control on windows.